Pyranylphenyl hydroxyalkylnaphthoic acids as inhibitors of...

C - Chemistry – Metallurgy – 07 – D

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C07D 309/10 (2006.01) A61K 31/19 (2006.01) A61K 31/35 (2006.01) A61K 31/38 (2006.01) A61K 31/535 (2006.01) C07C 65/17 (2006.01) C07C 65/24 (2006.01) C07D 265/30 (2006.01) C07D 295/096 (2006.01) C07D 295/155 (2006.01) C07D 295/24 (2006.01) C07D 309/06 (2006.01) C07D 309/30 (2006.01) C07D 335/02 (2006.01) C07D 491/08 (2006.01) C07D 493/08 (2006.01)

Patent

CA 2061706

Compounds having the formula I: (see formula I) are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis and allograft rejection and in preventing the formation of atherosclerotic plaques.

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