Pyranylphenyl naphthalene lactones as inhibitors of...

Details Pyranylphenyl naphthalene lactones as inhibitors of... Pyranylphenyl naphthalene lactones as inhibitors of...

C - Chemistry, Metallurgy

07

D

C07D 407/12 (2006.01) A61K 31/365 (2006.01) A61K 31/38 (2006.01) A61K 31/535 (2006.01) C07D 307/92 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 491/08 (2006.01) C07D 493/08 (2006.01)

Patent

CA 2061716

246/GL100 250/GL101 18315Y TITLE OF THE INVENTION PYRANYLPHENYL NAPHTHALENE LACTONES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS ABSTRACT OF THE DISCLOSURE Compounds having the formula I: Image I are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular:nephritis, hepatitis, endotoxemia, uveitis and allograft rejection and in preventing the formation of atherosclerotic plaques.

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