Pyrazine -2-carboxamide derivatives as mglur5 antagonists

Details Pyrazine -2-carboxamide derivatives as mglur5 antagonists Pyrazine -2-carboxamide derivatives as mglur5 antagonists

C - Chemistry, Metallurgy

07

D

C07D 241/26 (2006.01) A61K 31/4965 (2006.01) A61K 31/497 (2006.01) A61P 25/00 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2600169

The present invention is concerned with novel pyrazine 2-carboxyamide derivatives of the general formula (I) useful as metabotropic glutamate receptor antagonists: formula (I) wherein R1, R2 and R3 are as defined in the description and claims.

La présente invention concerne de nouveaux dérivés de pyrazine-2-carboxyamide de la formule générale (I), utiles en tant qu'antagonistes de récepteurs métabotropiques de glutamate : formule (I) où R1, R2 et R3 sont tels que définis dans la description et les revendications.

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