Pyrazinyl-substituted pyrrolo[2,3-b]pyridines, compositions...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/497 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2703125

The present invention relates to pyrazine substituted pyrrolopyridines which are inhibitors of JAK kinases (JAK1, JAK2, JAK3 and/or TYK2) and/or PDK1 and are thus useful for the treatment of myeloproliferative disorders or cancer.

La présente invention porte sur des pyrrolopyridines substituées par pyrazine qui sont des inhibiteurs de kinases JAK (JAKl, JAK2, JAK3 et/ou TYK2) et/ou PDKl, et qui sont ainsi utiles pour le traitement de troubles myéloprolifératifs ou du cancer.

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