Pyrazol-3-amines

Details Pyrazol-3-amines Pyrazol-3-amines

C - Chemistry, Metallurgy

07

D

167/238, 260/315

C07D 231/38 (2006.01) A61K 31/415 (2006.01)

Patent

CA 1305157

29 Abstract There are described compounds of formula I, Image I in which R1 represents hydrogen, alkyl, alkanoyl or alkyl substituted by Ar1, R3, R4 and R5, which may be the same or different, each independently represent hydrogen, alkyl or Ar3, Ar1, Ar2 and Ar3, which may be the same or different, independently represent phenyl or phenyl substituted by one or more of alkyl, hydroxy, alkoxy, NR6R7 or halogen, R6 and R7, which may be the same or different, independently represent hydrogen or alkyl, and pharmaceutically acceptable acid addition salts thereof. Compositions containing the compounds and methods for their preparation are also described. The compounds are indicated for use as pharmaceutical, eg anti-inflammatory, agents. 4804K(ir)/ac

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