C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/04 (2006.01) A61K 31/4439 (2006.01) A61K 31/444 (2006.01) C07D 401/14 (2006.01)
Patent
CA 2359462
The present invention is directed to compounds of formula (I) and pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising same, and to methods for inhibiting protein prenylation in an organism using the same, where R1, R2, R3, R4, R5, R6, R7 and X are defined herein.
La présente invention se rapporte à des composés représentés par la formule (I) et à des sels pharmaceutiquement acceptables de ces composés, à des compositions pharmaceutiques contenant ces composés et à des procédés d'inhibition de la prénylation des protéines dans un organisme au moyen de tels compositions. Les éléments R?1¿, R?2¿, R?3¿, R?4¿, R?5¿, R?6¿, R?7¿ et X de la formule (I) sont définis dans la description de l'invention.
Brown Bradley B.
Casey Patrick J.
Latona Zita
Purdy Janna C.
Tavares Sarah
Duke University
Johnson Ernest Peter
Pharmaco Investments Inc.
Ppd Discovery Inc.
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