Pyrazole derivative

Details Pyrazole derivative Pyrazole derivative

C - Chemistry, Metallurgy

07

D

C07D 401/14 (2006.01) A61K 31/444 (2006.01) A61K 31/496 (2006.01) A61K 31/497 (2006.01) A61K 31/501 (2006.01) A61K 31/506 (2006.01) A61K 31/5377 (2006.01) A61P 7/02 (2006.01) A61P 9/10 (2006.01) C07D 403/14 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2578261

A compound represented by the general formula (I): [wherein Ar1 represents the general formula (II): Ar2 represents an optionally substituted, 5- or 6- membered, aromatic heterocyclic group; and X represents the general formula (III)], a salt of the compound, or a solvate of either. Also provided is a potent platelet aggregation inhibitor which inhibits neither COX-1 nor COX-2.

Composé représenté par la formule générale (I) : [Formule chimique 1] [où Ar1 représente la formule générale (II) : [Formule chimique 2] Ar2 représente un groupement hétérocyclique aromatique de 5 ou 6 chaînons éventuellement substitué ; et X représente la formule générale (III)], [Formule chimique 3] sel du composé, ou solvat de l~un ou l~autre de ceux-ci. L~invention concerne également un inhibiteur puissant de l~agrégation des plaquettes qui n~inhibe ni COX-1, ni COX-2.

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