Pyrazole derivatives

C - Chemistry – Metallurgy – 07 – D

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167/10.2, 260/31

C07D 231/14 (2006.01) A01N 25/00 (2006.01) A01N 43/56 (2006.01) C07D 231/16 (2006.01) C07D 231/20 (2006.01)

Patent

CA 1077048

Abstract: Fungicidal compositions comprising as an active ingredient a compound of the general formula I Image wherein either R1 or R2 is the group -?NHR5 in which X is an oxygen atom or a sulphur atom and R5 is straight chain alkyl group of 1 to 8 carbon atoms, branched chain alkyl group of 1 to 8 carbon atoms, cyclic alkyl group of 3 to 8 carbon atoms, alkenyl group, alkynyl group, hydroxyalkyl group, phenyl group or a mono-, di- or tri- substituted phenyl group with sub- stituents, which may be the same or different, chosen from the group consisting hydrogen alkyl, alkenyl, alkynyl, hydroxy- alkyl, alkoxy, phenyl, halogen, trifluoromethyl, thiocyanate, nitro, cyano, amino, carboxy, alkoxycarbonyl, carbamoyl, N-alkylcarbamoyl and N,N-dialkylcarbamoyl; when R1 is the group -?NHR5 then R3 is hydrogen, alkyl, alkenyl alkynyl, hydroxyalkyl, phenyl, CH2CF3 or the group -CH2COOR6 wherein R6 is alkyl, phenyl or substituted phenyl, and R2 and R4, which may be the same or different, are hydrogen, alkyl, alkenyl, alkynyl, hydroxalkyl, alkoxy, phenyl, halogen, trifluoromethyl, thiocyanate, nitro, cyano, amino, carboxy, alkoxycarbonyl, carbamoyl, N,alkylcarbamoyl, N,N-dialkylcarbamoyl, hydroxy or mercapto provided that R2 and R4 are not both hydrogen, hydroxy or mercapto; when R2 is the group -?NHR5 then R3 is hydrogen, alkyl, alkenyl, alkynyl, hydroxyalkyl, phenyl or substituted phenyl, and R1 and R4, which may be the same or different, are hydrogen, alkyl, alkenyl, hydroxyalkyl, alkoxy, phenyl, substituted phenyl, halogen, trifluoromethyl, thio- cyanate, nitro, cyano, amino, carboxy, alkoxycarbonyl, carbamoyl, N-alkylcarbamoyl, N,N-dialkylcarbamoyl, hydroxy or mercapto, provided that R1 and R3 are not both hydrogen and provided that R1 and R4 are not both hydroxy or mercapto; and an inert carrier material therefor.

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