Pyrazole derivatives and their pharmaceutical use

Details Pyrazole derivatives and their pharmaceutical use Pyrazole derivatives and their pharmaceutical use

C - Chemistry, Metallurgy

07

D

C07D 231/40 (2006.01) A61K 31/415 (2006.01)

Patent

CA 2206201

The present invention relates to a pyrazole derivative represented by formula ( I ) or (II) : Image ( I ) Image (II) wherein R1 is hydrogen C2-C6 alkyl, benzyl or phenyl; each of R2 and R3 is hydrogen, C1-C6 alkyl or benzyl; each of R4 and R5 is hydrogen, C1-C6 alkyl, C3-C6 alkenyl, C3-C8 cycloalkyl, benzyl or phenyl; X is oxygen or sulfur; R5 is hydrogen, C2-C6 alkyl, C3-C6 alkenyl, C3-C8 cycloalkyl or benzyl when R1 is benzyl, R2 is ethyl, R3 is hydrogen, and R4 is hydrogen, and its pharmaceutical use.

L'invention porte sur un dérivé du pyrazole représenté par la formule (I) ou (II), Image (I) Image (II), où R1 est de l'hydrogène, un alkyle C2-C6, un benzyle ou un phényle; R2 et R3 sont de l'hydrogène, l'alkyle C1-C6 ou le benzyle; chacun de R4 et R5 est de l'hydrogène, un alkyle C1-C6, un alcényle C3-C6, un cycloalkyle C3-C8, un benzyle ou un phényle; X est de l'oxygène ou du soufre; R5 est de l'hydrogène, un alkyle C2-C6, un alcényle C3-C6, un cycloalkyle C3-C8 ou un benzyle; lorsque R1 est un benzyle, R2 est un éthyle, R3 et R4 sont de l'hydrogène; applications en pharmacie.

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