Pyrazole derivatives for treating conditions mediated by...

A - Human Necessities – 61 – K

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A61K 31/415 (2006.01) A61P 29/00 (2006.01) A61P 37/00 (2006.01) C07D 231/12 (2006.01) C07D 401/04 (2006.01) C07D 401/14 (2006.01) C07D 407/14 (2006.01) C07D 409/04 (2006.01)

Patent

CA 2572752

Compounds of formula (I) in free or salt form, wherein R1, R2, R3 and R4 have the meanings as indicated in the specification, are useful for treating a condition mediated by activation of the adenosine Alb receptor or the adenosine A3 receptor, particularly an inflammatory or obstructive airways disease. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.

Composés de formule (I) sous forme libre ou de sel, où R1, R2, R3 et R4 ont les significations indiquées dans la spécification, utiles pour traiter une pathologie médiée par l'activation du récepteur d'adénosine Alb ou du récepteur d'adénosine A3, en particulier une maladie inflammatoire ou obstructive des voies aériennes. Des compositions pharmaceutiques qui contiennent ces composés et des procédés pour préparer ces composés sont également décrits.

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