Pyrazole derivatives useful as cox-i inhibitors

Details Pyrazole derivatives useful as cox-i inhibitors Pyrazole derivatives useful as cox-i inhibitors

C - Chemistry, Metallurgy

07

D

C07D 231/12 (2006.01) C07D 231/14 (2006.01) C07D 231/18 (2006.01) C07D 231/22 (2006.01) C07D 231/24 (2006.01) C07D 401/04 (2006.01) C07D 403/10 (2006.01) C07D 403/14 (2006.01) C07D 413/04 (2006.01)

Patent

CA 2505945

A compound of the formula (I): (1) wherein R1 is hydrogen or lower alkyl; R2 is lower alkyl, etc.; R3 is lower alkoxy, etc. ; R4 is hydroxy, etc.; X is 0, S, etc.; Y is CH or N; Z is lower alkylene or lower alkenylene; and m is 0 or 1; or salts thereof, which are useful as a medicament.

L'invention concerne un composé de formule (I) ou des sels dudit composé utilisés comme médicament. Dans ladite formule, R?1¿ est hydrogène ou alkyle inférieur; R?2¿ est alkyle inférieur, etc.; R?3¿ est alcoxy inférieur, etc.; R?4¿ est hydroxy, etc.; X est 0, S, etc.; Y est CH ou N; Z est alkylène inférieur ou alcénylène inférieur; et m est 0 ou 1.

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