C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 231/12 (2006.01) A61K 31/415 (2006.01) A61K 31/454 (2006.01) C07D 231/14 (2006.01) C07D 231/56 (2006.01) C07D 401/12 (2006.01)
Patent
CA 2641441
This invention relates to compounds having pharmacological activity, to compositions containing these compounds, and to a method of treatment employing the compounds and compositions. More particularly, this invention concerns certain pyrazole derivatives, their salts and solvates. These compounds have H3 histamine receptor binding activity. This invention also relates to pharmaceutical compositions containing these compounds and to a method of treating disorders in which histamine H3 receptor modulation is beneficial.
La présente invention concerne des composés ayant une activité pharmacologique, des compositions contenant ces composés, et un procédé de traitement employant les composés et les compositions. Plus particulièrement, l'invention concerne certains dérivés de pyrazole, leurs sels et leurs solvates. Ces composés possèdent une activité de liaison au récepteur de l'histamine H3. L'invention concerne également des compositions pharmaceutiques contenant ces composés ainsi qu'un procédé de traitement de troubles dans lesquels la modulation du récepteur de l'histamine H3 est bénéfique.
Bennani Youseff L.
Campbell Michael G.
Dastrup David
Huck Emilie Porter
Athersys Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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