Pyrazolidinone cck and gastrin antagonists and...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 231/08 (2006.01) A61K 31/40 (2006.01) A61K 31/435 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 403/06 (2006.01) C07D 405/10 (2006.01) C07D 413/04 (2006.01) C07D 417/04 (2006.01)

Patent

CA 2046672

ABSTRACT OF THE DISCLOSURE The invention as described provides certain novel substituted pyrazolidinones which bind to receptors for cholecystokinin (CCK), and to receptors for gastrin. These compounds are CCK and gastrin antagonists, and are useful in the treatment and prevention of CCK and gastrin-related disorders, as well as modulation of the appetite regulatory systems of warm blooded vertebrates.

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