Pyrazoline compounds as mineralocorticoid receptor antagonists

Details Pyrazoline compounds as mineralocorticoid receptor antagonists Pyrazoline compounds as mineralocorticoid receptor antagonists

C - Chemistry, Metallurgy

07

D

C07D 231/54 (2006.01) A61K 31/416 (2006.01) A61K 31/4162 (2006.01) A61P 9/12 (2006.01) C07D 401/04 (2006.01) C07D 405/04 (2006.01) C07D 493/04 (2006.01)

Patent

CA 2667966

Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I: wherein R1, R2, R3A, R3B, R4, R5, R6, R7, R8, and X are as defined in the detailed description of the invention. Corresponding pharmaceutical compositions, methods of treatment, and intermediates are also disclosed.

L'invention concerne des composés et des sels pharmaceutiquement acceptables des composés, ces derniers ayant la structure représentée par la Formule I: dans laquelle R1, R2, R3A, R3B, R4, R5, R6, R7, R8 et X sont tels que définis dans la description détaillée de l'invention. L'invention concerne également des compositions pharmaceutiques correspondantes, des procédés de traitement correspondants et des intermédiaires correspondants.

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