C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61K 31/4545 (2006.01) A61P 1/00 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) A61P 7/00 (2006.01) A61P 9/08 (2006.01) A61P 9/10 (2006.01) A61P 11/06 (2006.01) A61P 17/06 (2006.01) A61P 19/02 (2006.01) A61P 19/08 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) A61P 37/02 (2006.01) A61P 43/00 (2006.01)
Patent
CA 2603457
A pyrazolo[1,5-a]pyridine derivative represented by the formula (I) and a medically acceptable salt thereof have an excellent MAPKAP-K2 inhibitory activity. Therefore, a pharmaceutical comprising the compound as an active ingredient is expected to be useful for the treatment or prevention of a MAPKAP-K2-mediated disorder such as an inflammatory disorder, an autoimmune disease, destructive osteopathy, cancer and/or tumor growth.
Un dérivé de pyrazolo[1,5-a]pyridine représenté par la formule (I) et un sel médicalement acceptable de celui-ci ont une excellente activité inhibitrice de MAPKAP-K2. De ce fait, on s'attend à ce qu'un produit pharmaceutique comprenant le composé comme ingrédient actif puisse être utile pour le traitement ou la prévention d~un trouble facilité par MAPKAP-K2 tel qu~un trouble inflammatoire, une maladie auto-immune, une ostéopathie destructrice, un cancer et/ou une croissance tumorale.
Hamada Motoko
Kataoka Kenichiro
Kosugi Tomomi
Makino Hiroaki
Matsueda Yohei
Borden Ladner Gervais Llp
Teijin Pharma Limited
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