Pyrazolo [1, 5-a] pyrimidines as cdk inhibitors

Details Pyrazolo [1, 5-a] pyrimidines as cdk inhibitors Pyrazolo [1, 5-a] pyrimidines as cdk inhibitors

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/52 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2653076

In its many embodiments, the present invention provides certain pyrazolo[1,5-a]pyrimidine compounds of Formula (I) which can have utility as inhibitors of cyclin dependent kinases ("CDKs") as well as methods of preparing such compounds. The compounds can have potential utility for the treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs.

Selon plusieurs modes de réalisation, la présente invention concerne certains composés pyrazolo[1,5-a]pyrimidines de formule (I) qui peuvent être utilisés en tant qu'inhibiteurs des kinases dépendantes de la cycline (CDK) ainsi que des procédés de préparation de tels composés. Les composés peuvent être utilisés pour assurer le traitement, la prévention, l'inhibition, ou l'amélioration d'une ou de plusieurs maladies associées aux CDK.

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