C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 25/00 (2006.01) A61P 35/00 (2006.01) C07D 231/00 (2006.01) C07D 239/00 (2006.01)
Patent
CA 2497544
In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
Dans ses nombreux modes de réalisation, la présente invention a trait à une classe nouvelle de composés pyrazolo[1,5-a]pyrimidine en tant qu'inhibiteurs des kinases dépendantes des cyclines, des procédés de préparation de ces composés, des compositions pharmaceutiques comprenant un ou plusieurs de tels composés, des procédés de préparation de formulations pharmaceutiques comprenant un ou plusieurs de ces composés, et des procédés de traitement, de prévention, d'inhibition, ou d'amélioration d'une ou des maladies liées à l'utilisation des kinases dépendantes des cyclines mettant en oeuvre de ces composés ou compositions pharmaceutiques.
Alvarez Carmen S.
Chan Tin-Yau
Dillard Lawrence W.
Doll Ronald J.
Dwyer Michael P.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Pharmacopeia Inc.
Pharmacopeia Drug Discovery Inc.
Schering Corporation
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