Pyrazolo[3,4-b]pyridin-2-yl]-benzoic acid derivatives as hiv...

Details Pyrazolo[3,4-b]pyridin-2-yl]-benzoic acid derivatives as hiv... Pyrazolo[3,4-b]pyridin-2-yl]-benzoic acid derivatives as hiv...

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61P 31/18 (2006.01)

Patent

CA 2612300

The present invention provides compounds of formula (I) wherein Cx represents - CHO, -CH=N-OR3, -CH=N-NR3R4, -CH=N-R5 or -CH(OR3)2; m and n can be present up to four times and the other R radicals can vary from a hydrogen atom to different alkyl groups, halogen, rings or more. These compounds are used in pharmaceutical compositions for the treatment or prevention of AIDS or HIV infection, or for reducing HIV replication.

La présente invention concerne des composés de formule (I), dans laquelle Cx représente -CHO, -CH=N-OR3, -CH=N-NR3R4, -CH=N-R5 ou -CH(OR3)2; m et n peuvent être présents quatre fois au maximum et les autres radicaux R peuvent varier d'un atome d'hydrogène à différents groupes alkyle, halogène, cycles ou autres. Ces composés sont utilisés dans des compositions pharmaceutiques pour traiter ou prévenir le SIDA ou une infection à VIH ou pour diminuer une réplication du VIH.

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