Pyrazolo¬4,3-c|pyridines, a process for their preparation...

Details Pyrazolo¬4,3-c|pyridines, a process for their preparation... Pyrazolo¬4,3-c|pyridines, a process for their preparation...

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/435 (2006.01)

Patent

CA 2108941

Abstract Pyrazolo[4,3-c]pyridines, a process for their preparation and their use as serotonin reuptake inhibitors The invention relates to compounds of the frmula Image (I) wherein Ar is Image or pyridyl; R1 is H,-(CH2)pNR2R3, Image , Image or Image ; R2 is hydrogen or loweralkyl; R3 is hydrogen or loweralkyl; R4 is hydrogen or loweralkyl; X and Y are independently halogen, trifluoromethyl, nitro, loweralkyl, loweralkoxy or hydroxy; n is 0,1,2 or 3; m is 0,1 or 2; p and q are independently 2, 3 or 4, or a pharmaceutically acoeptable addition salt and/or hydrate thereof, or where applicable, a geometric or optical isomer or racemic mixture thereof. This invention also relates to a process for making the compounds and to pharmaceutical compositions, and to their use as serotonin reuptake inhibitors.

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