Pyrazolo[4,3-d]pyrimidin-5-yl) derivative used as pde5...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 487/04 (2006.01) A61K 31/505 (2006.01) A61P 9/12 (2006.01) A61P 13/12 (2006.01) A61P 25/00 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2629339

The present invention comprises (I) 1-(1-(2-ethoxyethyl-3-ethyl-7-(4- methylpyridin-2- ylamino)-lH-pyrazolo[4,3-d]pyrimidin-5-yl)piperidine-4- carboxylic acid and its salts. The invention further comprises pharmaceutical compositions, methods of treatment, and synthetic methods relating to Formula (I). Formula (I) is used to inhibit the PDE5 enzyme.

La présente invention concerne un acide 1-(1-(2-éthoxyéthyl-3-éthyl-7-(4-méthylpyridin-2- ylamino)-lH-pyrazolo[4,3-d]pyrimidin-5-yl)pipéridine 4-carboxylique représenté par la formule (i) et ses sels. L'invention concerne également des compositions pharmaceutiques, des méthodes de traitement et des procédés de synthèse concernant la formule (I). L'acide représenté par la formule (I) et ses sels s'utilisent pour inhiber l'enzyme PDE5.

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