Pyrazolo[4,3-d] pyrimidine derivatives useful as pde-5...

C - Chemistry – Metallurgy – 07 – D

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C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 3/00 (2006.01) A61P 9/00 (2006.01) A61P 9/12 (2006.01) A61P 15/00 (2006.01) A61P 25/00 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2585557

This invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5 and R5 and R6 are as described herein,which are cyclic guanylate monophosphate (cGMP)-specific phosphodiesterase type 5 inhibitors (PDE-5 inhibitors) that are useful in the treatment of hypertension and other disorders, to processes for their preparation, intermediates used in their preparation, to compositions containing them and the uses of said compounds and compositions.

L'invention concerne des composés de formule (I). Dans cette formule, R1, R2, R3, R4, R5 et R6 sont décrits dans la description.

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