C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 35/00 (2006.01) C07D 487/14 (2006.01)
Patent
CA 2526578
Pyrazolo-quinazoline derivatives of formula (Ia) or (Ib) as defined in the specification, and pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer.
L'invention concerne des dérivés de pyrazolo-quinazoline de formule (Ia) ou (Ib), tels que définis dans la spécification, des sels pharmaceutiquement acceptables de ces dérivés, un procédé pour les préparer et des compositions pharmaceutiques les contenant. Les composés de la présente invention s'avèrent utiles en thérapie, dans le traitement de maladies associées à un dérèglement de l'activité protéine kinase comme le cancer.
Brasca Maria Gabriella
D'alessio Roberto
Fancelli Daniele
Ferguson Ron
Panzeri Achille
Nerviano Medical Sciences S.r.l.
Pharmacia & Italia S.p.a.
Smart & Biggar
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