Pyrazolone compounds as metabotropic glutamate receptor...

C - Chemistry – Metallurgy – 07 – D

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C07D 231/22 (2006.01) A61P 25/28 (2006.01) C07D 231/20 (2006.01)

Patent

CA 2591003

Compounds of Formula (I), wherein R1, R2, R3, R4, R5, R6, X, and n are as defined for Formula (I) in the description, processes for the preparation of the compounds and new intermediates employed in the preparation, pharmaceutical compositions containing the compounds, and the use of the compounds in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction.

La présente invention concerne des composés ayant la formule (I), dans laquelle R1, R2, R3, R4, R5, R6, X et n sont tels que définis pour la formule (I) dans la description, des procédés de préparation desdits composés et de nouveaux produits intermédiaires utilisés pour ladite préparation, des compositions pharmaceutiques contenant lesdits composés et l~utilisation desdits composés pour le traitement ou la prévention de troubles neurologiques et psychiatriques associés au dysfonctionnement glutamatergique.

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