A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4152 (2006.01) A61P 25/00 (2006.01)
Patent
CA 2576544
A drug including edaravone for the treatment of cerebrovascular disorders associated with insufficient cerebral circulation such as ischemic stroke, which comprises a pharmaceutically effective amount of a pyrazolone compound of structural Formula (I): or a pharmaceutically acceptable salt thereof, or a pseudo-polymorphic form thereof, administered at a controlled dose so that the plasma concentration of unchanged form is kept constant for a predetermined period of time and so that the compound may exhibit a higher effect.
L'invention concerne un médicament destiné au traitement de troubles cérébrovasculaires à une circulation cérébrale insuffisante tels que l'accident ischémique cérébral, lequel contient une dose pharmaceutique efficace d'un composé de pyrazolone ayant la formule structurale (I) ou bien un sel pharmaceutiquement acceptable de celui-ci, ou une forme pseudo-polymorphe de celui-ci, administré à une dose réglée de sorte que la concentration dans le plasma de la forme non modifiée est gardée constante pendant une durée prédéterminée, et de telle sorte que le composé peut présenter un effet supérieur.
Nakano Takuma
Suzuki Hiroko
Yuki Satoshi
Kirby Eades Gale Baker
Mitsubishi Pharma Corporation
Mitsubishi Tanabe Pharma Corporation
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