Pyrazolopyridine compound and processes for preparation thereof

Details Pyrazolopyridine compound and processes for preparation thereof Pyrazolopyridine compound and processes for preparation thereof

C - Chemistry, Metallurgy

07

D

167/211, 260/251

C07D 471/04 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2008263

There are described pyrazolopyridine compounds of the formula: Image wherein R1 is aryl, and R2 is unsaturated heterocyclic group which may have one or more suitable substituent(s), and pharmaceutically acceptable salts thereof. Also described are the process for preparing these compounds, pharmaceutical compositions containing them and their uses for the treatment of melancholia, heart failure, hypertension, renal insufficiency, edema, obesity, bronchial asthma, gout, hyperuricemia, sudden infant death syndrome, immunosuppression, diabetes, myocardiac infarction, thrombosis, obstruction, arteriosclerosis obliterans, thrombophlebitis, cerebral infarction, transient ischemic attack or angina pectoris.

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