Pyrazolopyridine derivatives

Details Pyrazolopyridine derivatives Pyrazolopyridine derivatives

C - Chemistry, Metallurgy

07

D

260/273, 260/241

C07D 471/04 (2006.01) C07D 231/16 (2006.01) C07D 231/38 (2006.01)

Patent

CA 1242714

Abstract A compound of formula (I) or a pharmaceutically acceptable salt thereof: Image (I) wherein: R1 is hydrogen, C1-6 alkyl or phenyl optionally substituted by halogen, CF3, C1-4 alkoxy or C1-4 alkyl; R2 is hydrogen or C1-6 alkyl; R3 is C2-10 alkenyl or C1-10 alkyl substituted by hydroxy, C1-4 alkoxy, thiol, C1-4 alkylthio or NR7R8 wherein R7 and R8 are independently hydrogen or C1-6 alkyl or together are C3-6 polymethylene; R4 and R5 are independently hydrogen or C1-4 alkyl; and R6 is hydroyen; or C1-4 alkyl or benzyl attached at nitrogen atom 1 or 2, having anti-inflammatory and/or anti-allergy activity, a process for their preparation and their use as pharmaceuticals.

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