Pyrazolopyridines and analogs thereof

Details Pyrazolopyridines and analogs thereof Pyrazolopyridines and analogs thereof

C - Chemistry, Metallurgy

07

D

C07D 471/14 (2006.01) A61K 31/437 (2006.01) A61K 31/4375 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2540598

Pyrazolopyridin-4-amines, pyrazoloquinolin-4-amines, pyrazolonaphthyridin-4- amines, and 6,7,8,9-tetrahydropyrazoloquinolin-4-amines, pharmaceutical compositions containing the compounds, intermediates, and methods of use of these compounds as immunomodulators, for inducing or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases, are disclosed.

L'invention concerne des pyrazolopyridin-4-amines, des pyrazoloquinoléin-4-amines, des pyrazolonaphthyridin-4-amines et des 6,7,8,9-tétrahydropyrazoloquinoléin-4-amines, des préparations pharmaceutiques contenant lesdits composés, des intermédiaires et des méthodes d'utilisation de ces composés en tant qu'immunomodulateurs, pour l'induction ou l'inhibition de la biosynthèse de la cytokine chez des animaux, et dans le traitement de maladies, dont des maladies néoplasiques et virales.

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