Pyrazolopyrimidinone cgmp pde5 inhibitors for the treatment...

C - Chemistry – Metallurgy – 07 – D

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C07D 487/04 (2006.01) A61K 31/505 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) A61K 31/55 (2006.01) C07D 231/14 (2006.01) C07D 231/40 (2006.01) C07D 401/12 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2287552

There is provided compounds of formula IA and of formula IB, (see formula I) (see formula II) wherein R1, R2, R3, R4 and A have meanings given in the description, which are useful in the curative and prophylactic treatment of a medical condition for which inhibition of a cyclic guanosine 3',5'-monophosphate phosphodiesterase (e.g. cGMP PDE5) is desired.

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