Pyrazolopyrimidinone cgmp pde5 inhibitors for the treatment...

Details Pyrazolopyrimidinone cgmp pde5 inhibitors for the treatment... Pyrazolopyrimidinone cgmp pde5 inhibitors for the treatment...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/519 (2006.01) C07D 231/00 (2006.01) C07D 231/14 (2006.01) C07D 239/00 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2347950

There is provided compounds of formula (IA) and of Formula (IB), wherein R1, R2, R3, R4 and A have meanings given in the description, which are useful in the curative and prophylactic treatment of medical conditions for which inhibition of a cyclic guanosine 3',5'-monophosphate phosphodiesterase (e.g. cGMP PDE5) is desired.

L'invention concerne les composés représentés par les formules (IA) et (IB), dans lesquelles R<1>, R<2>, R<3>, R<4> et A sont utiles pour le traitement préventif et curatif de pathologies pour lesquelles l'inhibition de la phosphodiestérase d'acide guanosine 3',5'- monophosphate cyclique (par exemple, cGMP PDE5) est désirée.

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