C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/4162 (2006.01) A61P 25/28 (2006.01)
Patent
CA 2687765
The invention provides compounds of Formula (I) wherein A, Y, R1, R1a, R2, and R2a are as described in the specification. Compounds of Formula I are useful in treating and/or preventing cognitive disorders, such as Alzheimer 's disease. The invention also encompasses pharmaceutical compositions comprising compounds of Formula (I), methods of preparing compounds of Formula (I), and methods of treating cognitive disorders, such as Alzheimer's disease.
L'invention concerne des composés de formule I (I) dans laquelle A, Y, R1, R1a, R2 et R2a sont tels que décrits dans le mémoire. Les composés de formule I sont utiles dans le traitement et/ou la prévention de troubles cognitifs, tels que la maladie d'Alzheimer. L'invention concerne également des compositions pharmaceutiques comprenant des composés de formule I, des procédés de préparation de composés de formule I et des procédés de traitement de troubles cognitifs, tels que la maladie d'Alzheimer.
Bowers Simeon
Dressen Darren
Garofalo Albert W.
Hom Roy K.
Mattson Matthew N.
Borden Ladner Gervais Llp
Elan Pharmaceuticals Inc.
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