C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/438 (2006.01) A61P 35/00 (2006.01) C07D 491/04 (2006.01) C07D 495/04 (2006.01)
Patent
CA 2641776
Compounds of Formula (I) inhibit the PARP enzyme and are useful for treating a disease or a disorder associated with PARP. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I), methods of treatment comprising compounds of Formula (I), and methods of inhibiting the PARP enzyme comprising compounds of Formula (I).
La présente invention concerne des composés répondant à la formule (I) inhibant l'enzyme PARP et utiles dans le traitement d'une pathologie ou d'un trouble associés à PARP. Elle concerne également des compositions pharmaceutiques comprenant des composés répondant à la formule (I), des procédés de traitement comprenant des composés répondant à la formule (I) et des procédés d'inhibition de l'enzyme PARP comprenant des composés répondant à la formule (I).
Gandhi Virajkumar B.
Giranda Vincent L.
Gong Jianchun
Penning Thomas D.
Zhu Gui-Dong
Abbott Laboratories
Torys Llp
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