Pyrazolospiroketone acetyl-coa carboxylase inhibitors

Details Pyrazolospiroketone acetyl-coa carboxylase inhibitors Pyrazolospiroketone acetyl-coa carboxylase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 491/20 (2006.01) A61K 31/438 (2006.01) A61P 1/16 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2724774

The invention provides compounds of Formula (1) or a pharmaceutically acceptable salt of said compound, wherein R1, R2, and R3 are as described herein; pharmaceutical compositions thereof; and the use thereof in treating diseases, conditions or disorders modulated by the inhibition of acetyl-CoA carboxylase enzyme(s) in an animal.

La présente invention concerne des composés de formule (1) ou un sel pharmaceutiquement acceptable dudit composé, dans laquelle R1, R2, et R3 sont tels que décrits ici; l'invention concerne également des compositions pharmaceutiques de ceux-ci; et l'utilisation de ceux-ci dans le traitement de maladies, de conditions ou de troubles modulés par l'inhibition del'enzyme ou des enzymes acétyl-CoA carboxylase chez un animal.

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