Pyridazine compounds and methods

Details Pyridazine compounds and methods Pyridazine compounds and methods

C - Chemistry, Metallurgy

07

D

C07D 237/26 (2006.01) A61K 31/50 (2006.01) A61K 31/5377 (2006.01) C07D 403/12 (2006.01) C07D 413/06 (2006.01)

Patent

CA 2589102

The invention relates to novel chemical compounds, compositions and methods of making and using the same. In particular, the invention provides pyridazine compounds and/or related heterocyclic derivatives, compositions comprising the same, and methods of using pyridazine compounds and/or related heterocyclic derivatives and compositions comprising the same, for modulation of cellular pathways (e.g., signal transduction pathways), for treatment or prevention of inflammatory diseases (e.g., Alzheimer's disease), for research, drug screening, and therapeutic applications.

L'invention concerne de nouveaux composés chimiques, des compositions et leurs méthodes de préparation et d'utilisation. Plus particulièrement, l'invention concerne des composés pyridazine et/ou des dérivés hétérocycliques associés, des compositions les comprenant ainsi que des méthodes d'utilisation de composés pyridazine et/ou de dérivés hétérocycliques associés et de compositions les comprenant pour la modulation des voies cellulaires (par ex., voies de transduction de signaux), pour le traitement ou la prévention de maladies inflammatoires (par ex., la maladie d'Alzheimer), pour la recherche, pour le criblage de médicaments et pour d'autres applications thérapeutiques.

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