C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 237/00 (2006.01) A01N 43/58 (2006.01) A61K 31/4965 (2006.01) A61K 31/50 (2006.01) C07D 237/02 (2006.01) C07D 403/00 (2006.01) C07D 405/00 (2006.01) C07D 409/00 (2006.01)
Patent
CA 2589106
The invention relates to novel chemical compounds, compositions and methods of making and using the same. In particular, the invention provides pyridazine compounds and/or related heterocyclic derivatives, compositions comprising the same, and methods of making and using pyridazine compounds and/or related heterocyclic derivatives and compositions comprising the same, for modulation of cellular pathways (e.g., signal transduction pathways), for treatment or prevention of inflammatory diseases (e.g., Alzheimer's disease), for research, drug screening, and therapeutic applications.
L'invention concerne des nouveaux composés chimiques, des compositions et des procédés de production et d'utilisation de ceux-ci. L'invention concerne en particulier des composés pyridazine et/ou des dérivés hétérocycliques associés, des compositions comprenant ceux-ci, et des procédés de production et d'utilisation desdits composés pyridazine et/ou des dérivés hétérocycliques associés et des compositions comprenant ceux-ci, pour la modulation de voies cellulaires (par exemple, des voies de transduction de signaux), pour le traitement ou la prévention de maladies inflammatoires (par exemple, la maladie d'Alzheimer), la recherche, le criblage de médicaments, et des applications thérapeutiques.
Bourguignon Jean-Jacques
Haiech Jacques
Hibert Marcel
Hu Wenhui
Van Eldik Linda
Centre National de La Recherche Scientifique (cnrs)
Mccarthy Tetrault Llp
Northwestern University
Universite de Strasbourg
Universite Louis Pasteur de Strasbourg
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