Pyridazine derivatives and their use as therapeutic agents

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 237/20 (2006.01) A61K 31/501 (2006.01) A61P 3/06 (2006.01) C07D 237/24 (2006.01)

Patent

CA 2533899

Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I), where x, y, W, V, R2, R3, R4, R5, R6, R6a, R7, R7a, R8, R8a, R9 and R9a are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.

L'invention concerne des procédés de traitement d'une maladie ou d'une condition induite par SCD chez un mammifère, de préférence un être humain, ce procédé consistant à administrer à un mammifère le nécessitant un composé représenté par la formule (I). Dans cette formule x, y, W, V, R?2¿, R?3¿, R?4¿, R?5¿, R?6¿, R?6a¿, R?7¿, R?7a¿, R?8¿, R?8a¿, R?9¿ et R?9a¿ y sont définis. L'invention concerne également des compositions pharmaceutiques comprenant les composés représentés par la formule (I).

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