Pyridazine derivatives and their use as therapeutic agents...

A - Human Necessities – 61 – K

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A61K 31/501 (2006.01) A61K 9/00 (2006.01) A61K 47/08 (2006.01) A61K 47/10 (2006.01) A61K 47/32 (2006.01) A61P 17/00 (2006.01) A61P 17/08 (2006.01) A61P 17/10 (2006.01)

Patent

CA 2716336

Methods of treating an SCD-mediated skin disorder or condi-tion in a mammal, preferably a human, including administering to a mammal in need thereof a compound of formula (I): where x, y, W, V, R2, R3, R4, R5, R6, R6a, R7, R7a, R8, R8a, R9 and R9a are defined herein, and compositions including a compound of formula (I).

Linvention concerne des méthodes de traitement dune affection ou dun trouble cutané à médiation par SCD chez un mammifère, de préférence un humain, comprenant ladministration à un mammifère qui en éprouve la nécessité, dun composé de formule (I) : dans laquelle x, y, W, V, R2, R3, R4, R5, R6, R6a, R7, R7a, R8, R8a, R9 et R9a sont définis ici, et des compositions qui comprennent le composé de formule (I).

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