A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/501 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) A61P 43/00 (2006.01) C07D 237/24 (2006.01)
Patent
CA 2580845
Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I) where x, y, G, J, K, L, M, Q, W, V, R2, R3, R5, R5a, R6, R6a, R7, R7a, R8 and R8a are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.
Procédés de traitement d'une maladie ou d'un état pathologique à médiation par SCD chez un mammifère, de préférence chez un humain; ces procédés comprennent l'administration à un mammifère nécessitant un tel traitement d'un composé correspondant à la formule (I) dans laquelle x, y, G, J, K, L, M, Q, W, V, R2, R3, R5, R5a, R6, R6a, R7, R7a, R8 et R8a sont définis dans l'invention. L'invention concerne aussi des compositions pharmaceutiques comprenant les composés correspondant à la formule (I).
Chowdhury Sultan
Fu Jian-Min
Kamboj Rajender K.
Kodumuru Vishnumurthy
Sviridov Serguei V.
Gowling Lafleur Henderson Llp
Xenon Pharmaceuticals Inc.
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