Pyridazinone compounds

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 403/14 (2006.01) A61K 31/501 (2006.01) A61P 25/18 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2751565

The present invention provides a compound which has the effect of PDE inhibition, and which is useful as a medicament for preventing or treating schizophrenia or so on. A compound of formula (I0), wherein R1 represents a substituent; R2 represents a hydrogen atom, or a substituent; R3 represents a hydrogen atom, or a substituent; Ring A represents an aromatic ring which can be substituted, and Ring B represents a 5-membered heteroaromatic ring which can be substituted,or a salt thereof.

La présente invention concerne un composé qui exerce un effet d'inhibition de PDE, et qui est utile comme médicament pour prévenir ou traiter la schizophrénie ou des maladies similaires. Elle concerne un composé de formule (I0), dans laquelle R1 représente un substituant; R2 représente un atome d'hydrogène, ou un substituant; R3 représente un atome d'hydrogène, ou un substituant; le cycle A représente un cycle aromatique qui peut être substitué, et le cycle B représente un cycle hétéroaromatique à 5 chaînons qui peut être substitué, ou l'un de ses sels.

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