Pyridazinone compounds and p2x7 receptor inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 237/20 (2006.01) A61K 31/50 (2006.01) A61K 31/501 (2006.01) A61P 29/00 (2006.01) A61P 37/00 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 407/12 (2006.01) C07D 407/14 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2699631

Novel pyridazinone compounds of formula (I), which inhibit the purinergic P2X7 receptor and are useful for prevention, therapy and improvement of inflammatory and immunological diseases.

L'invention porte sur de nouveaux dérivés de pyridazinone de la formule (I) qui inhibent le récepteur purinergique P2X7 et sont utiles pour la prévention, la thérapie et l'amélioration de maladies inflammatoires et immunologiques.

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