Pyridazinone derivative and pde inhibitor containing the...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 401/14 (2006.01) A61K 31/501 (2006.01) A61P 1/00 (2006.01) A61P 9/04 (2006.01) A61P 9/10 (2006.01) A61P 9/12 (2006.01) A61P 11/00 (2006.01) A61P 11/06 (2006.01) A61P 11/16 (2006.01) A61P 17/00 (2006.01) A61P 17/04 (2006.01) A61P 19/02 (2006.01) A61P 25/00 (2006.01) A61P 25/16 (2006.01) A61P 25/24 (2006.01) A61P 25/28 (2006.01) A61P 27/16 (2006.01) A61P 29/00 (2006.01) A61P 37/08 (2006.01) A61P 43/00 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 4

Patent

CA 2692248

It is to provide a novel pyridazinone derivative represented by the following general formula (1), which is useful as a pharmaceutical and has a phosphodiesterase inhibitory action: Image wherein R1 represents H or C1-6 alkyl, each of R2 and R3 represents H, X, C1-6 alkoxy, Z represents O or S, and A represents AA or BB, wherein AA represents: Image and BB represents: Image wherein R4 represents H or C1-6 alkyl, and each of R5 and R6 represents C1-6 alkyl. -338-

La présente invention concerne un nouveau dérivé de pyridazinone représenté par la formule générale (1) ci-dessous, qui est utile comme produit pharmaceutique ayant une activité inhibitrice de la phosphodiestérase.

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