Pyridazinone derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 403/04 (2006.01) A61K 31/501 (2006.01) A61P 25/00 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01)

Patent

CA 2744489

The present invention is concerned with novel pyridazinone derivatives of formula (I) wherein R1, R2, R3 and R4 are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds inhibit PDE10A and can be used as medicaments.

La présente invention concerne de nouveaux dérivés de pyridazinone de formule (I) dans laquelle R1, R2, R3 et R4 sont tels que définis dans la description et dans les revendications, ainsi que leurs sels et esters physiologiquement acceptables. Ces composés inhibent PDEA10 et peuvent être utilisés comme médicaments.

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