Pyridazinone derivatives and processes for preparing the same

Details Pyridazinone derivatives and processes for preparing the same Pyridazinone derivatives and processes for preparing the same

C - Chemistry, Metallurgy

07

D

C07D 237/14 (2006.01) A61K 31/50 (2006.01) A61K 31/535 (2006.01) C07D 237/04 (2006.01) C07D 401/02 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 403/02 (2006.01) C07D 403/06 (2006.01) C07D 403/12 (2006.01) C07D 409/00 (2006.01) C07D 409/04 (2006.01) C07D 409/06 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01) C07D 413/02 (2006.01) C07D 413/12 (2006.01) C07D 417/02 (2006.01) C07D 417/08 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2099743

Abstract: Disclosed are a pyridazinone compound represented by the formula: Image (I) wherein (1) R1 is a substituted or unsubstituted C1-10 alkyl, a C3-6 cycloalkyl, a lower alkenyl, a hetero- cyclic group having N, O or S atom or camphor-10-yl; R3 is hydrogen, a substituted or unsubstituted lower alkyl or a lower alkenyl; or R1 and R3 are bonded at terminal ends thereof to form a lower alkylene; and Z is a group represented by the formula: Image where n is 1 or 2; and D is hydrogen or a halogen; or (2) R1 is a substituted or unsubstituted C1-10 alkyl, a substituted or unsubstituted phenyl, a C3-6 cyclo- alkyl, a lower alkenyl, a heterocyclic group having N, O or-S atom or camphor-10-yl; R3 is hydrogen, a sub- stituted or unsubstituted lower alkyl or a lower alkenyl ; or R1 and R3 are bonded at terminal ends thereof to form a lower alkylene; and Z is a group represented by the formula: Image ; and R2 is hydrogen, a substituted or unsubstituted lower alkyl, an aryl or a lower alkenyl; and -A-B- is an ethylene or vinylene each of which may be substituted by 1 or 2 groups selected from the group consisting of a lower alkyl and phenyl group, or a pharmaceutically acceptable salt thereof, and proc- esses for preparing the same.

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