C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 237/04 (2006.01) A61K 31/50 (2006.01) C07D 237/14 (2006.01) C07D 237/16 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 409/06 (2006.01)
Patent
CA 2283399
The invention encompasses the pyridazin-3-one compounds of formula (I) as well as a method of treating cyclooxygenase-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of formula (I). The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of formula (I).
L'invention se rapporte à des composés de pyridazine-3-one, représentés par la formule (I), et à un procédé de traitement de maladies à médiation par cyclo-oxygénase-2. Le procédé consiste à administrer une quantité non toxique et pharmaceutiquement efficace d'un composé de formule I à un patient nécessitant un tel traitement. L'invention concerne également certaines compositions pharmaceutiques destinées au traitement de maladies à médiation par cyclo-oxygénase-2, qui contiennent des composés de formule (I).
Gauthier Jacques Y.
Lau Cheuk K.
Li Chung Sing
Prasit Petpiboon
Therien Michel
Merck Frosst Canada & Co./merck Frosst Canada & Cie
Merck Frosst Canada Ltd.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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