Pyridine-2,4- and 2,5-dicarboxamides, a process for the...

A - Human Necessities – 61 – K

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A61K 31/44 (2006.01) C07D 213/81 (2006.01) C07D 213/86 (2006.01)

Patent

CA 2030633

- 1 - HOE B9/F 369 Abstract of the disclosure: Pyridine-2,4- and 2,5-dicarboxamides, a process for the preparation thereof, and the use thereof The invention relates to pyridine-2,4- and -2,5-dicarbox- amides of the formula I (I) Image in which R1 has the stated meaning. The compounds according to the invention inhibit the enzyme proline hydroxylase or lysine hydroxylase and can accordingly be used as fibrosuppressants and immuno- suppressants.

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