Pyridine and pyrimidine derivatives as phosphodiesterase 10...

Details Pyridine and pyrimidine derivatives as phosphodiesterase 10... Pyridine and pyrimidine derivatives as phosphodiesterase 10...

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/4184 (2006.01) A61P 3/00 (2006.01) A61P 25/18 (2006.01) C07D 401/14 (2006.01) C07D 417/12 (2006.01) C07D 471/04 (2006.01) C07D 473/00 (2006.01)

Patent

CA 2742833

Pyridine and pyrimidine compounds, and compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive- compulsive disorder, and the like.

L'invention concerne des composés de pyridine et de pyrimidine, des compositions les contenant, et des processus de préparation de ces composés. L'invention concerne en outre des procédés permettant de traiter des troubles ou des maladies que l'on peut traiter par inhibition de PDE10, par exemple l'obésité, les diabètes non insulino-dépendants, la schizophrénie, le trouble bipolaire, le trouble obsessionnel compulsif, etc.

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