Pyridine compounds having a fused cycloalkane ring...

C - Chemistry – Metallurgy – 07 – D

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C07D 215/48 (2006.01) C07D 221/04 (2006.01) C07D 221/16 (2006.01)

Patent

CA 1040636

Abstract The invention relates to a process for preparing pyridine compounds which have a fused cycloalkane ring con- taining an amide, thioamide or nitrile group. The process involves treating a metal derivative of the pyridine compound with a silyl isocyanate or isothiocyanate and then subjecting the product to hydrolysis. The compounds of the invention display pharmacological activity, namely anti-uncler and/or anti-secretory activity.

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