Pyridine compounds with basic substituents, a process for...

Details Pyridine compounds with basic substituents, a process for... Pyridine compounds with basic substituents, a process for...

C - Chemistry, Metallurgy

07

D

260/278.2, 260/2

C07D 401/12 (2006.01) C07D 213/74 (2006.01) C07D 213/80 (2006.01) C07D 213/85 (2006.01) C07D 213/89 (2006.01) C07D 401/14 (2006.01)

Patent

CA 1256873

HOE 85/F 259 Abstract: A process for the manufacture of a pyridine compound of the formula I Image (I) in which R1 and R2 independently of each other represent hydrogen or alkyl having from 1 to 4 carbon atoms, R3 represents hydrogen or alkyl having up to 2 carbon atoms and A represents alkylene having 2 to 4 carbon atoms, n is 0 or 1, Z is a group of the formula Za, Zb or Zc Image (Za) Image (Zb) Image (Zc) in which either R4 is hydrogen and R5 is phenyl or cinnamyl or R4, R5, R7 and R8 independently of each other are pyridyl, phenyl or phenyl which is substituted by up to 2 equal or different substituents from the group halogen and alkoxy having up to 2 carbon atoms, R6 is hydrogen or hydroxy and X is hydrogen, a cyano, amino or nitro group or the group -CO-R9, in which R9 is hydroxy or alkoxy having from 1 to 4 carbon atoms, and of the physiologically tolerable salts of these compounds,

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