Pyridine derivative and pharmaceutical containing the same

Details Pyridine derivative and pharmaceutical containing the same Pyridine derivative and pharmaceutical containing the same

C - Chemistry, Metallurgy

07

D

C07D 213/75 (2006.01) A61K 31/44 (2006.01) C07D 213/64 (2006.01) C07D 213/643 (2006.01) C07D 213/82 (2006.01) C07D 405/12 (2006.01)

Patent

CA 2322953

A pyridine derivative represented by formula (1) [wherein R represents a halogen atom or a halogen-substituted lower alkyl; R2 and R3 respectively represent a hydrogen atom or a halogen atom; V represents a group: -C(=O)NH-, -NHC(=O) or NH-; and A represents A1, A2 or A3: (groups in A1 to A3 respectively represent a hydrogen atom, a lower alkyl, a lower alkanoyl, hydroxyl, benzoyl or an oxo group)] or a pharmaceutically acceptable salt thereof. The compound (1) inhibits collagen production and is useful for preventing or treating fibrosis.

L'invention concerne un dérivé de pyridine représenté par la formule (1) [dans laquelle R<1> représente un atome d'halogène ou un alkyle inférieur substitué par l'halogène; R<2> et R<3> représentent respectivement un atome d'hydrogène ou un atome d'halogène; V représente un groupe: -C(=O)NH-, -NHC(=O) ou NH-; et A représente A<1>, A<2> ou A<3>: (II) (les groupes de A<1> à A<3> représentent respectivement un atome d'hydrogène, un alkyle inférieur, un alcanoyle inférieur, l'hydroxyle, le benzoyle ou un groupe oxo)] ou un sel pharmaceutiquement acceptable de ce dérivé. Le composé (1) inhibe la production de collagène et est utile pour le traitement préventif ou curatif de la fibrose.

Affiliated with

Also associated with

Rating

Pyridine derivative and pharmaceutical containing the same does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pyridine derivative and pharmaceutical containing the same, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pyridine derivative and pharmaceutical containing the same will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1821762