Pyridine derivatives having angiotensin ii antagonism

Details Pyridine derivatives having angiotensin ii antagonism Pyridine derivatives having angiotensin ii antagonism

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/395 (2006.01) C07D 213/62 (2006.01) C07D 213/64 (2006.01) C07D 213/65 (2006.01) C07D 213/68 (2006.01) C07D 213/69 (2006.01) C07D 213/70 (2006.01) C07D 213/72 (2006.01) C07D 213/78 (2006.01) C07D 213/80 (2006.01) C07D 221/04 (2006.01) C07D 401/10 (2006.01) C07D 401/14 (2006.01)

Patent

CA 2051705

The invention provides compounds represented by the following formula (I) (See formula I) or a pharmaceutically acceptable salts thereof wherein A represents (See formulas II, III, IV) B represents a carboxy or tetrazolyl group; and X represents -O-, -NH- or -S(O)t-. The compounds possess angiotensin II antagonism, and may be used as an antihypertensive agent, a therapeutic agent to congestive heart failure, an antianxiety agent and a cognitive enhancing agent.

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