Pyridine derivatives, their production and use

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 417/12 (2006.01) A61K 31/44 (2006.01) A61K 31/505 (2006.01) A61K 31/535 (2006.01) C07D 213/68 (2006.01) C07D 213/70 (2006.01) C07D 213/81 (2006.01) C07D 213/82 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01) C07D 413/12 (2006.01) C07D 417/14 (2006.01) C07D 473/00 (2006.01)

Patent

CA 2068255

Abstract of the disclosure: PYRIDINE DERIVATIVES, THEIR PRODUCTION AND USE There is disclosed a pharmaceutical composition for providing antiinflammatory, antipyretic, analgesic, antiallergic, immunosuppressing or immunomodulating activity which comprises a pyridine derivative of the formula (I): Image (I) wherein R is an optionally substituted pyridine ring, X is a oxygen atom or -S(O)n-, wherein n is 0, 1 or 2, A is a bivalent C1-15 hydrocarbon residue whose branched moiety may have a substituent, Y is an oxygen or sulfur atom, R3 is a hydrogen atom or an optionally substituted hydrocarbon residue, R4 is an optionally substituted hydrocarbon residue or an optionally substituted monocyclic or bicyclic heterocyclic group, R3 and R4 may be joined together with the carbamoyl group or the thiocarbamoyl group to which they are attached to form an optionally substituted heterocyclic group, or R3 or R4 may be independently attached to A to form a ring, or a pharmaceutically acceptable salt or solvate thereof, and a pharmaceutically acceptable carrier or diluent.

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